Donald P Cameron Selected Research

RNA Polymerase I (Polymerase I, RNA)

1/2020	rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461.
1/2019	First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.
1/2017	Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.
1/2017	Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
11/2016	The Dual Inhibition of RNA Pol I Transcription and PIM Kinase as a New Therapeutic Approach to Treat Advanced Prostate Cancer.

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Donald P Cameron Research Topics

Disease

7	Neoplasms (Cancer) 01/2020 - 08/2016
2	Hematologic Neoplasms (Hematological Malignancy) 01/2020 - 11/2016
2	Melanoma (Melanoma, Malignant) 01/2018 - 07/2014
1	Infections 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2020
1	Lymphoma (Lymphomas) 01/2019
1	Leukemia 01/2017
1	African Trypanosomiasis (Nagana) 01/2017
1	Carcinogenesis 11/2016
1	Prostatic Neoplasms (Prostate Cancer) 11/2016
1	Genomic Instability 02/2015

Drug/Important Bio-Agent (IBA)

6	CX 5461IBA 01/2020 - 08/2016
5	RNA Polymerase I (Polymerase I, RNA)IBA 01/2020 - 11/2016
3	Ribosomal DNA (rDNA)IBA 01/2020 - 01/2019
2	Ribosomal RNAIBA 01/2020 - 11/2016
2	ChromatinIBA 01/2020 - 01/2019
2	palbociclibIBA 01/2018 - 07/2014
1	Type II DNA Topoisomerases (Topoisomerase II)IBA 01/2021
1	Deubiquitinating EnzymesIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2018
1	BMH-21IBA 01/2017
1	proto-oncogene proteins pimIBA 11/2016
1	Phosphotransferases (Kinase)IBA 11/2016
1	RNA (Ribonucleic Acid)IBA 11/2016
1	CX-6258IBA 11/2016
1	Histones (Histone)IBA 02/2015
1	Transcription Factors (Transcription Factor)IBA 02/2015
1	Retinoblastoma ProteinIBA 07/2014
1	Proteins (Proteins, Gene)FDA Link 07/2014

Therapy/Procedure

2	Therapeutics 01/2020 - 01/2018
1	Drug Therapy (Chemotherapy) 01/2017
1	Oral Administration 11/2016
1	Castration 11/2016